About rdvg


rdvg developed in Dr. Mullins Lab at University of Washington is a web interface to assess a phylogenetic tree for evidence of latent viral reservoirs. It inputs a newick tree with branch lengths, difined reservoir and non-reservoir sequences and number of random simulation testing, outputs the P value and rd values of the test and random simulations.

Newick tree with branch lengths
A tree file in newick format. The tree must have branch lengths.

Example for newick tree with branch lengths:

((((((((((((a:0.00612000,b:0.00595500):0.01387200,c:0.01541200):0.01137700,((d:0.00893100,e:0.00854900):0.00682500,f:0.00684900):0.00199800):0.00000000,((g:0.02244900,((h:0.00345900,i:0.00515800):0.00706400,(j:0.00169600,k:0.00342400):0.00164900):0.00427000):0.00169100,l:0.01615600):0.00462800):0.00199400,(m:0.01245800,n:0.01418600):0.00353400):0.01074400,o:0.01140200):0.00864400,(p:0.00000000,q:0.00168400):0.01595200):0.01238600,(r:0.01226800,s:0.01613900):0.00124300):0.00201200,(t:0.05447700,u:0.01046900):0.00444700):0.05659400,OG1:0.12043000):0.04544800,og2:0.16630300):0.04016250,(og3:0.18159100,og4:0.11105600):0.02776250);

Replication file
A list of user defined reservoir sequence names which must match the sequence names in newick tree.

Example for replication file:

a
b
c
d
e
f
g
h
i
j
k

Non-replication file
A list of user defined non-reservoir sequence names which must match the sequence names in newick tree.

Example for non-replication file:

l
m
n
o
p

Number of random simulations
The number that user inputs to simulate rd by randomly shuffling the nodes in the tree.

We would like to have your comments after your using this tool. Please give your feedback to webmaster.